What is EGF?

epidermal growth factoror EGF (Eng. Epidermal Growth Factor,) is a factor in the regeneration of epidermal cells, belongs to the group of growth factors (cytokines) and is a polypeptide. It belongs to the most stable of all studied proteins. Present in the cells of all tissues of the body, regulates cell growth.

Epidermal growth factor was discovered by Stanley Cohen (1986 Nobel Prize in Physiology or Medicine) and Rita Levi-Montalcini. In 1962, Stanley Cohen and Rita Levi-Montalcini discovered a new thermostable protein in the tissues of the submandibular salivary glands of mice that had the ability to treat conjunctivitis and gingivitis in these animals. Tests «in vitro» on skin and epithelial tissues confirmed the fact that this substance stimulates cell growth. In other words, EGF able to slow down the aging process of skin cells and give a «second youth». Research EGF continue uninterruptedly, many cosmetic products and treatments with the factor EGF.

However, there are many questions associated with it. In this article, let’s get to know EGF take a closer look and see what to expect from him!

How does EGF work in cosmetics?

Under normal conditions, the content of growth factors in the human body is relatively low and stable. But with any damage, for example, wounds, the number of receptors sensitive to epidermal growth factor increases in the wound cavity, due to this, the concentration of EGF increases. But under conditions of deteriorating ecology, with malnutrition, anemia, infection and dysfunction of various organs, regulatory processes are disrupted, a sufficient amount of EGF is not produced, so the healing of injuries takes much longer and is much less effective.

As you know, with age, the natural synthesis of growth factors in the epidermis decreases. This leads to loss of tone and thinning of the skin.

Growth factors in cosmetics start the process of skin renewal:

  • enhance the synthesis of their own collagen and elastin;
  • increase density;
  • increase elasticity;
  • reduces wrinkles;
  • brightens pigmentation;
  • accelerate the healing of cracks, wounds and other skin lesions.

Also, clinical trials have proven that EGF improves the growth of epithelial, endothelial and fibroblast cells, improves tissue proliferation and cell chemotaxis; reduces the likelihood of infection, the growth of scar tissue, reduces the healing time, the period of disability; restores the normal functioning of tissues after damage.

Thus, cosmetics with EGF can really have a pronounced rejuvenating effect on the skin!

How to recognize the epidermal growth factor in the composition?

Many manufacturers include this truly magical ingredient in their anti-aging products. It is hidden behind the following «synonyms»: EGF, Epidermal Growth Factor, Human Epidermal Growth Factor (hEGF), HGF, Human Epidermal Growth Factor, rh-Oligopeptide-1 (instead of 1 there may be other numbers), sh-Oligopeptide-1, sh-Polypeptide-1, rh-Polypeptide-1, transforming growth factor TGF.

Where is EGF found?

If in European cosmetics EGF is contained in products, mainly expensive, from a number of selective or professional cosmetics, then in Japanese and Korean cosmetics EGF is included everywhere. It is found in many anti-wrinkle products: anti-aging creams, serums, hydrogel patches, sheet masks, BB creams, and even moisturizing mists.

This component has long been adopted by brands that produce middle-level cosmetics and even the mass market. These are no longer ampoules from professional cosmetics, but ordinary creams for daily care. Common but effective.

EGF growth factors work even at a minimum concentration — from 0.1%. Therefore, in the compositions they are most often in one of the last places. Do not think that this makes them less effective!

Also, let’s not forget that in addition to the growth factor, anti-aging cosmetics contain other active ingredients: snail mucin, collagen, adenosine, matrixyl and other peptides. Working together, they provide an even more pronounced «rejuvenating» result.

The range of the online store includes products containing EGF. Next, we will describe the most popular of them:

Hydrogel eye patches with gold and EGF Petitfee Gold EGF Eye & Spot Patch

Designed for all skin types of women and girls 25+. Suitable for use both for the eye contour and local facial care (lip corners, temples, between the eyebrows, etc.)

Colloidal gold evens out the skin, promotes its regeneration.

EGF actively protects skin cells from harmful external influences and promotes their normal growth.

Natural extracts saturate the skin with beneficial vitamins and microelements.

Caviar extract promotes skin elasticity, strengthens and tightens it.

Elizavecca Milky Piggy Hell-Pore Water Up Peptide EGF Mist One Button Anti-Aging & Hydrating Spray Mask

Innovative peptide complex Milky Piggy Hell-Pore Water Up Peptide EGF Mist One Button is a convenient spray-mask based on effective ingredients that allows you to apply a mask on your face with one click.

The composition of the mist includes growth factorswhich stimulate active cell division, due to which they renew the skin, increase the production of collagen and elastin, increase density, and promote skin rejuvenation at the cellular level.

Mist nourishes and deeply moisturizes the skin, fights pigmentation, helping to get rid of freckles and age spots. When applied, it quickly soothes the skin, relieves redness and itching, facilitates recovery from inflammatory processes. The components of the spray quickly penetrate into the deeper layers of the skin, actively soften it, smooth out fine wrinkles and even help to get rid of some scars or scars.

Aomi Black Pearl-EGF Hydrogel Eye Patch

Intensively moisturize and tone the skin, improve blood circulation in the capillaries, promote muscle relaxation and the reproduction of its own collagen.

Aomi patches are developed using special Asian technology and consist of natural high-nutrient substances.

The tool fits snugly to problem areas, which contributes to the deep penetration of active ingredients into the skin.

The composition includes pearl extract, which prevents the synthesis of melanin, preventing the formation of age spots and freckles, increases skin elasticity, and has an anti-inflammatory effect.

Epidermal growth factor EGF slows down the aging process and reduces pigmentation, promotes the renewal of epidermal cells, preserves youthful skin, improves complexion.

Elizavecca Face Care CF-Nest 97% B-jo Serum

Serum with swallow’s nest extract Elizavecca Cf-Nest 97% B-Jo Serum will preserve your youth and beauty, emphasize your femininity and attractiveness.

The special formula includes Swallow’s Nest Enzyme and EGF acting at the cellular and molecular levels. Interestingly, in Asia, swallows build nests from algae, eggs and fry, holding it all together with saliva. Thanks to this, the nest is enriched with valuable trace elements.

Swallow’s nest extract incomparably rejuvenates the face, improves skin condition: refreshes it, makes it soft, velvety, radiant. This component intensively nourishes and moisturizes tissues, restores their firmness and elasticity, models the oval of the face and improves its color, has a lifting effect, and gives a well-groomed appearance.

Holika Holika Prime Youth EGF Mask Sheet

The mask has an anti-inflammatory effect, prevents the formation of age spots, helps to normalize the fat balance, moisturizes and nourishes, restores elasticity, and is a prevention of aging. The special cut of the product provides the effect of a snug fit, and the large area of ​​​​the fabric guarantees full coverage. There are also special pockets for working out the area around the eyes.

Mask for active regeneration of the epidermis Elizavecca Egf Deep Power Ringer Mask Pack

Mask for active regeneration of the epidermis Elizavecca Egf Deep Power Ringer Mask Pack is especially effective for severe skin problems.

Active ingredients: hyaluronic acid, swallow’s nest extract, witch hazel, peach, purslane, strawberry, plum, watermelon, arginine, adenosine — have the most beneficial effect.

Night cream with a high content of mucin and bee venom Benton Snail Bee High Content Steam Cream

Cream with a high content of snail mucin and bee venom Benton Snail Bee High Content Steam Cream is a therapeutic product that will quickly bring dry and dehydrated skin back to life. The product has a comfortable texture and is intended for nightly restoration of the epidermis. The product has moisturizing, nourishing and whitening properties. Its formula is enriched with adenosine and arbutin, which increase the elasticity of the skin surface and prevent the formation of wrinkles.

The active ingredients of the cream are Snail Secrection snail mucus extract (64%), rejuvenating EGF peptide, bee venom and hyaluronic acid, which harmoniously interact with each other, tighten the skin and eliminate signs of fading!

Try products with EGF — and see for yourself the effectiveness of this powerful ingredient!


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